Drug may boost leukemia response to chemo while protecting heart | News World

A targeted gene therapy may make acute myeloid leukemia more sensitive to chemotherapy, while also protecting the heart against toxicity often caused by cancer treatments, a study with mice shows.

Acute myeloid leukemia (AML) is the most common type of leukemia in adults and the resulting chemotherapy treatment can put patients at an increased risk for cardiac damage.

Xunlei Kang, associate professor of medicine at the University of Missouri, and PhD students Yi Pan and Chen Wang led a study looking at similarities between leukemia and cardiovascular disease. They found a shared target—aAGTR1, a receptor responsible for cell reproduction—was overabundant in the blood cells of patients with leukemia.

The researchers used losartan, a common medicine for treating high blood pressure, to inhibit the AGTR1 receptor in mice. This disrupted cancer growth, slowing the development of leukemia, and led to longer survival. The next step is to further investigate losartan’s effectiveness in treating human leukemia…

Advertisement Gaming:   Xbox  |  Xbox Bundles  |  Nintendo  |  Playstation  |  Cards   | 
FTC: We use income earning affiliate links. More on Sposored links.
Terms of use and third-party services. More here.
Ad Amazon Minecraft the game, plus clothing, toys, and accessories.
Ad Amazon Gaming Laptops, clothing, games and more
Ad Amazon MUSIC Artists Merch Shop

Prime members enjoy Prime FREE One-Day delivery

Related Posts