Research finds causal evidence tying cerebral small-vessel disease to Alzheimer’s, dementia | News World

Research led by in part by The University of Texas Health Science Center at San Antonio (UT Health San Antonio) finds that the most common cerebral small-vessel disease feature seen in brain magnetic resonance imaging is a primary vascular factor associated with dementia risk.

Results of the major international study emphasize the significance of that feature, known as white matter hyperintensity (WMH) burden, in preventive strategies for dementia.

“Our findings provide converging evidence that WMH is a major vascular factor associated with dementia risk,” said Muralidharan Sargurupremraj, PhD, an assistant professor at the Glenn Biggs Institute for Alzheimer’s and Neurodegenerative Diseases at UT Health San Antonio. “They also support WMH as a surrogate marker for clinical trials to prevent dementia by controlling vascular risk.”

Sargurupremraj is the first and co-corresponding author of the research, titled, “Genetic Complexities of Cerebral Small Vessel Disease, Blood Pressure,…

Source www.sciencedaily.com

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